N-Substd.-4,4-dimethyl-isoquinolin-1,3-diones - as hypotensive agents also showing bradycardisant, antiarythmic and sedative effects

摘要

Isoquinolines and their salts have the formula: (where R1 is H, Hal, MeO or MeS, R2 is H or MeO, n is 2 or 3, A is R3 = H or Me, R4 is pyridyl opt. substd. by Me or Ph opt. substd. by Cl, CF3, one or two, Me, Et or MeO, and R5 and R6 are H or MeO). (I) are useful as hypotensive agents but also showing bradycardisant, anti-arythmic and sedative effects.