THE OCULAR HYPOTENSIVE EFFECTS OF LUMIGAN ARE UNRELATED TO MET - ABOLITE FORMATION

摘要

Lumigan (Bimatoprost) is a synthetic prostamide analog with a pharmacology profile that is distinct from prostaglandins. Lumigan is also a potent and highly efficacious ocular hypotensive a-gent over a 0.001% - 0.1% dose range. To closely represent events that would occur in human subjects who receive Lumigan, two ocular distribution and metabolism studies on Lumigan