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A semisintetic procedure for the preparation of vincristine. (Machine-translation by Google Translate, not legally binding)
A semisintetic procedure for the preparation of vincristine. (Machine-translation by Google Translate, not legally binding)
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机译:制备长春新碱的半科学程序。 (通过Google翻译进行机器翻译,没有法律约束力)
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摘要
A semi-synthetic process for the preparation of vincritine in which vimblastine or a salt thereof, preferably sulphate, is oxidized with chromic acid or with one of its salts at low temperature, the reaction mixture is neutralized or alkalized and the product it is separated by extraction, the extract is evaporated to dryness, the dried residue is optionally formylated, vincristine and optionally also N-demethyl-vimblastine are isolated from the product and the product or products are optionally converted into its salts, preferably in the sulfates . (Machine-translation by Google Translate, not legally binding)
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