N-(heteroaryl-methyl)-6,14-(endoethano or endoetheno)-7- hydroxyalkyl-tetrahydro-nororipavines or-northebaines and salts thereof

摘要

Compounds of the formulaPPWHEREINP PR. sub.1 is hydrogen, methyl or acetyl,PPR.sub.2 is hydrogen or methyl,PPR.sub.3 is hydrogen, methyl, n- propyl, phenethyl or phenyl,PPR.sub.4 is hydrogen or methyl, PPZ is --CH=CH-- or --CH.sub.2 --CH.sub.2 --, andP PY is oxygen or sulfur,PPAND NON- TOXIC, PHARMACOLOGICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF; THE COMPOUNDS AS WELL AS THEIR SALTS ARE USEFUL AS ANALGESICS AND ANTITUSSIVES.