Preparation of octahydro-1,3,5,7-tetraalkanoyl-1,3,5,7- tetrazocines

摘要

Octahydro-1,3,5,7-tetraalkanoyl-1,3,5,7-tetrazocines are produced by acting a methylene-bis-alkanecarboxamide with formaldehyde. The reaction carried out by heating the reactants in the presence of an acidic catalyst an inert organic liquid under substantially anhydrous conditions.