Process for separating proteins from central nervous system tissue and treating experimentally induced demyelinating diseases

摘要

There is described a process for the preparation and separation of components from central nervous system tissue by sequential chromatography; wherein certain components contain proteins of a weight average molecular weight of 8,000 to 10,000 and are highly encephalitogenic while others have weight average molecular weights in the range of 2,000 to 4,000 and exhibit weaker encephalitogenic activity, and in addition, a method of treating experimentally induced diseases by administering said low molecular weight components is described.