A procedure for the preparation of indian derivatives. (Machine-translation by Google Translate, not legally binding)

摘要

A process for the preparation of indan derivatives of formula I. **(See formula)** where X represents a hydrogen atom or a halogen atom; R1 and R2, the same or different, each represent a C1-C5 lower alkyl group or a C3-C7 cycloalkyl group, at least one of the radicals R1 and R2 being a hydrogen atom; Y represents the radical = COOH and R3 = H, characterized in that it is carried out on a ketone of the formula: **(See formula)** a Willgerodt reaction by action of a primary or secondary amine of formula NHR5R6, to give a thioamide of formula: **(See formula)** where R1, R2, R5, R6 and X have the meaning given above and subsequent acid hydrolysis to obtain the desired product. (Machine-translation by Google Translate, not legally binding)