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Circulatory-active phenylethylamine derivs - from bis-(3,4-dimethoxy-6-methylphenylethyl)-hexamethylenediamine and boronitro-bromide
Circulatory-active phenylethylamine derivs - from bis-(3,4-dimethoxy-6-methylphenylethyl)-hexamethylenediamine and boronitro-bromide
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机译:循环活性苯乙胺衍生自双-(3,4-二甲氧基-6-甲基苯乙基)-六亚甲基二胺和硼硝基溴化物
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摘要
Phenylethylamine derivs. are of formula (I):- (where R1 = lower alkyl; R2 = H, lower alkyl or hydroxymethyl; n = 2-10), and salts with inorganic- and organic acids. (I) are pref. N,N'-bis-(3,4-dihydroxy-6-methylphenylethyl)-hexamethylenediamine and acid-addition salts, and are prepd. from bis-(3,4-dimethoxy-6-methylphenylethyl)-hexamethylenediamine and boronitro bromide. (I) may be used in the treatment of hypertension, in shock therapy, in cases of acute kidney failure connected with hypertension.
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机译:苯乙胺衍生物。通式(I)的化合物是:(其中R 1 =低级烷基; R 2 = H,低级烷基或羟甲基; n = 2-10),以及与无机和有机酸形成的盐。 (I)是首选。 N,N′-双-(3,4-二羟基-6-甲基苯基乙基)-六亚甲基二胺和酸加成盐被制备。由双-(3,4-二甲氧基-6-甲基苯基乙基)-六亚甲基二胺和硼硝基溴。 (I)可用于治疗高血压,休克疗法,与高血压有关的急性肾衰竭。
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