PHARMACEUTICAL COMPOSITION OF NEUROPROTECTIVE ACTION FOR PARENTERAL APPLICATION ON BASIS OF HEXAMETHYLENEDIAMINE BIS-(N-MONOSUCCINYL-L-GLUTAMIL-L-LYSINE) IN LYOPHILIZED DOSAGE FORM

摘要

FIELD: medicine; pharmacy.SUBSTANCE: invention relates to medicine and pharmacy and relates to a pharmaceutical composition of neuroprotective action in the form of a lyophilisate for the manufacture of injection or infusion dosage forms containing as an active ingredient hexamethylenediamine bis-(N-monosuccinyl-L-glutamyl-L-lysine) and lyoprotectants and cryoprotectants in a certain quantitative ratio of the components used as functional additives, when using the recommended modes of drying and freezing.EFFECT: implementation of the invention allows to create a stable dosage form, optimal for storage and use, and also to receive the preparation providing increase in duration of a finding of a dipeptide in a system blood-groove in comparison with its substance.5 cl, 4 tbl, 11 ex