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new bicyclic compounds having the main skeleton of the - methylene - oxa -, 9 - diazabicyclo (4,2,2) decane
new bicyclic compounds having the main skeleton of the - methylene - oxa -, 9 - diazabicyclo (4,2,2) decane
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机译:主要骨架为-亚甲基-氧杂-,9-二氮杂双环(4,2,2)癸烷的新型双环化合物
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摘要
Case 4-10641/+ Canada Bicyclomycin derivatives (i.e. compounds with the skeleton of the 5-methylene-2-oxa-7,9-diazabicyclo¢4,2,2!decane) of the formula (I) wherein Ra to Rd represent hydrogen atoms or hydroxyl protective groups, X represents a free or functionally modified carboxyl group, a substituted or unsubstituted hydrocarbon radical or a halogen atom, and n is 0 or 1, possess valuable antibiotic properties which are of importance in particular for combating infections caused by Enterobacteriaceae and Proteus species.
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