Di:methyl-amino-isopropyl-4-acylamino benzoate derivs. - prepd. by acylation or esterification and used to improve learning-ability and memory

摘要

Dimethylamino isopropyl-4-acylamino benzoates of formula (I) and acid-addn. salts are new: (where R is aliphatic, aromatic or heterocyclic acyl). (I) aid the cellular metabolism and are useful in geriatry to improve learning ability and memory. A typical cpd. is dimethylamino ispropyl 4-nicotinamide benzoate which was prepd. from 13.8 parts nicotinoyl chloride hydrochloride and 25.8 parts dimethyl amino isopropyl p-amino benzoate hydrochloride in 50 parts pyridine at 100 degrees C. The yield was 31 parts.