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derivatives of carboxylic acids aziridin - 2 - n - substituted with immunomodulating activities, processes for their preparation and medicines containing these substances.
derivatives of carboxylic acids aziridin - 2 - n - substituted with immunomodulating activities, processes for their preparation and medicines containing these substances.
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机译:具有免疫调节活性的叠氮基羧酸-2-n-羧酸衍生物,其制备方法和含有这些物质的药物。
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摘要
A 2-cyanaziridine derivative of the formula IMAGE wherein R' is a straight-chained or branched, saturated or mono- or polyunsaturated aliphatic hydrocarbon radical with up to 8 carbon atoms, which is substituted by an aromatic nitrogen-containing heterocyclic radical with 5 or 6 ring-members and 1, 2 or 3 nitrogen atoms optionally substituted by halogen, alkoxy with up to 8 carbon atoms, alkyl with up to 8 carbon atoms, hydroxyl, carbalkoxy with up to 9 carbon atoms, carbamoyl, dialkylamino the alkyl moieties of which having up to 8 carbon atoms, cycloalkylamino, the cycloalkyl moiety having 3-10 carbon atoms, acetylamino, nitro, cyano, acetyl, alkylthio with up to 8 carbon atoms, alkylsulphinyl with up to 8 carbon atoms, alkylsulphonyl with up to 8 carbon atoms, sulphamoyl, phenyl, trifluoromethyl, phenoxy, acetoxy or methylenedioxy; or a pharmacologically acceptable salt thereof, exhibits immune stimulating activity.
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