Synthesis of 6-sulfamoyl-4-oxoquinoline-3-carboxylic acid derivatives as integrase antagonists with anti-HIV activity

摘要

一系列新奇 6-sulfamoyl-4-oxoquinoline-3-carboxylic 酸衍生物为 HIV integrase 抑制活动被综合了并且屏蔽。他们的结构被 ESIMS 证实， 1 H NMR 和 13 C NMR。