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Process for the preparation of a strain of influenza virus and use of this strain for the production of live viral vaccines against influenza
Process for the preparation of a strain of influenza virus and use of this strain for the production of live viral vaccines against influenza
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机译:制备流感病毒毒株的方法以及该毒株在生产抗流感活病毒疫苗中的用途
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摘要
The strain P/76/7 of influenza virus, resistant to serum inhibitors, is obtained by recombining the strains A/PR8/34 and A/Victoria/3/75 of influenza virus with each other and by subjecting the strain resulting from the recombination to three passages through the allantoic cavity of embryonated eggs in the presence of normal guinea-pig serum. A live anti-influenza vaccine is obtained by incubating this serum inhibitor-resistant strain in the allantoic cavity of embryonated eggs, by harvesting the viral material and by freeze-drying it.
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