Haemagglutinin of haemophilus gallinarum, process for its production, this haemagglutinin vaccine containing and its use for combating of huehnercoryza

摘要

PURPOSE:To provide hemagglutinin of Haemophilus gallimarum, useful as prophylactic vaccine and antibody (anti-serum) for remedy of infections chicken coryza. CONSTITUTION:A hemagglutinin which is a protein having fibrous structure and containing subunits having a molecular weight of about 39.000 measured by SDS PAGE method, loses its antigen activity and hemagglutination activity by heating at 100 deg.C for 5 min. and keeps its hemagglutination activity by heating at 70 deg.C for=5 min. and is eluted near the V0 value of Sepharose 6B. It can be prepared by treating cultured cells of Haemophilus gallinarum with trypsin.