No structural change due to G228S substitution of haemagglutinin in emerging H6N1 influenza virus

摘要

To the editor,Sir,in later 2013,the newest emerging influenza infection is firstly reported from Taiwan[1,2].This newest cross species influeza is called H6N1 bird flu[1,2].Genetic mutation is believed to be the cause of cross species infection and the G228S substitution of haeniagglutinin is proposed for increasing the mutant affinity for the humanα2-6 linked sialic acid receptor[3].This mechanism is believed to