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3-Acyl-4-ethyl-2-oxazolones and oxazolidinones
3-Acyl-4-ethyl-2-oxazolones and oxazolidinones
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机译:3-酰基-4-乙基-2-恶唑酮和恶唑烷酮
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摘要
This invention relates to the preparation of optically active d-2- aminobutanol by catalytic asymmetric reduction of appropriate dehydro precursors to produce selectively the desired isomer. The same substrates can also be used to prepare the dl-mixture using optically inactive catalysts. The novel substituted-4-ethyl-4-oxazolin-2-one and substituted- 4-ethyl-2-oxazolidinone compounds of this invention are useful as intermediates in the production of the antituberculosis drug ethambutol (Myambutol®).
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