PROCESS FOR THE PRODUCTION OF PROTECTED THREO-3-AMINO ACID 2-HYDROXY-4-OXOBUTANOIC OR ITS ESTERS AND APPLICATION TO THE PRODUCTION OF THREO-3-AMINO-2-HYDROXYBUTANOIC ACID

摘要

P THE PRESENT INVENTION IS A PROCESS FOR THE PRODUCTION OF THREO-3 AMINO 2-HYDROXYBUTANOIC ACID OR ITS ESTERS. /P P THIS PROCESS CONSISTS OF REACTING N-PROTECTED 2-OXOETHYLAMINE WITH A COMPOUND OF FORMULA: BR/ (CF DRAWING IN BOPI) BR/ IN WHICH: R IS A NAPHTYL GROUP OR A GROUP: BR/ (CF DRAWING IN BOPI) BR/ OR R AND R ONT A DEFINED MEANING, WITH GLYOXYLIC ACID OR ITS ESTERS, IN ORDER TO PRODUCE THREO-3-AMINO PROTECTED 2-HYDROXY-4-OXOBUTANOIC ACID OR ITS ESTERS, THEN REDUCING THIS COMPOUND TO THREO-3-AMINO ACID PROTECTS 2-HYDROXYBUTANOIC OR ITS ESTERS. /P P APPLICATION OF THESE COMPOUNDS, PARTICULARLY TO THE PREPARATION OF THREO-3-AMINO-2 HYDROXYBUTANOIC ACID. /P