首页> 外国专利> method for the preparation of the substance exchange working product, a purine 3 ', 5' - cyclofosfaatverbinding contains.molded product obtained by application of the method and procedure for the preparation of a purine 3 ', 5' - cyclofosfaatverbinding,suitable for use in the method for the preparation of a medicine.

method for the preparation of the substance exchange working product, a purine 3 ', 5' - cyclofosfaatverbinding contains.molded product obtained by application of the method and procedure for the preparation of a purine 3 ', 5' - cyclofosfaatverbinding,suitable for use in the method for the preparation of a medicine.

机译:物质交换工作产物的制备方法,嘌呤3',5'-环磷酰胺的结合物,通过应用嘌呤3',5'-环磷酰胺的结合方法和步骤得到的成型产品,适用于制备药物的方法。

摘要

Nucleotides of formula (I) where A=H, OH, or (if X=Br) NH2, B=H or NH2 Y=H or OH, and X=hal, OH, an ether residue SH, a thioether residue, or opt subst. NH2. have similar physiological properties to adenosine-3',5'-cyclic phosphate (II) but with greater enzymic resistance, and an increased lipolytic/glycogenolytic activity ratio, (I) are prepd. pref. from I (X=H), by halogenation, and opt. replacement of the halogen.
机译:式(I)的核苷酸,其中A = H,OH或(如果X = Br)NH 2,B = H或NH 2,Y = H或OH,且X = hal OH,醚残基SH,硫醚残基或选择替代。氨气具有与3',5'-环磷酸腺苷(II)相似的生理特性,但具有较高的酶抗性,并且脂解/糖原分解活性比(I)提高。偏好通过卤化得到I(X = H),并选择。替代卤素。

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