首页> 外国专利> method for preparation of a preparation with an anti - arrhythmic effect, which is an active ingredient in a form suitable for such preparations,formed preparations obtained by application of the method and process for preparation of a pro product with an anti arrhythmic effect suitable for re - use this procedure.

method for preparation of a preparation with an anti - arrhythmic effect, which is an active ingredient in a form suitable for such preparations,formed preparations obtained by application of the method and process for preparation of a pro product with an anti arrhythmic effect suitable for re - use this procedure.

机译:具有抗心律失常作用的制剂的制备方法,其是适合于这种制剂的形式的活性成分,通过应用该方法获得的成型制剂和制备具有抗心律失常作用的原产品的方法-使用此过程。

摘要

Isoindolin-1-one derivatives substituted on the nitrogen atom in the 2-position by an unsubstituted or substituted phenyl radical or a heterocyclic radical having aromatic characteristics, substituted in the 3-position by a 3-amino(or substituted amino)-2-hydroxypropoxy group, and optionally substituted in the 5- and/or 6-positions by one or two alkoxy radicals or optionally substituted in the 5- and 6-positions by a methylenedioxy radical, possess pharmacodynamic properties, and are especially useful as antiarrhythmic agents.
机译:异吲哚啉-1-一衍生物在2-位氮原子上被未取代或取代的苯基或具有芳香族特性的杂环基取代,在3-位被3-氨基(或取代的氨基)-2-取代羟基丙氧基,其任选地在一个5和/或6-位被一个或两个烷氧基取代,或任选地在5-和6-位被一个亚甲二氧基取代,具有药效学性质,并且特别用作抗心律不齐药。

著录项

  • 公开/公告号NL168510B

    专利类型

  • 公开/公告日1981-11-16

    原文格式PDF

  • 申请/专利权人 RHONE-POULENC S.A. TE PARIJS.;

    申请/专利号NL19730003291

  • 发明设计人

    申请日1973-03-08

  • 分类号C07D209/48;A61K31/395;C07D401/04;C07D403/04;C07D491/02;

  • 国家 NL

  • 入库时间 2022-08-22 13:43:49

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