ANALYTICAL OR CLINICAL DERIVATIVES, TAGGED DERIVATIVES AND METHODS OF ANALYSIS USING SUCH DERIVATIVES

摘要

ABSTRACT OF THE DISCLOSURENovel isocyanates such as, for example, blockedL-tyrosine methyl ester isocyanate, are reacted with com-pounds of biological, clinical interest or the like suchas, for example, digoxin, to form derivatives respectiveto tagging, as by radiolabeling The tagged derivativesmay then be employed to determine the presence of acompound of interest in nanomolar or even picomolar amountsby using clinical analysis techniques such as radio-immunoassay.