首页>
外国专利>
A liver-cell proliferation stimulating factor and medicines containing this factor as active ingredient
A liver-cell proliferation stimulating factor and medicines containing this factor as active ingredient
展开▼
机译:肝细胞增殖刺激因子和含有该因子作为有效成分的药物
展开▼
页面导航
摘要
著录项
相似文献
摘要
A factor which causes an increase in the number of liver cells through increased cell division activity, obtained by homogenizing the remaining livers of partially hepatectomized animals, subjecting the homogenate to acidification to pH=5.5 and then heat treatment at 95 DEG C., and centrifuging said homogenate. After such treatment, the factor is contained in the supernatant. The factor is a neuraminic-acid-free protein with a molecular weight of approximately 30,000 to 50,000 D. An extract containing the factor also can be obtained from the blood plasma of hepatectomized animals, when the plasma in addition to the described steps further is treated with neuraminidase. Similarly, an extract containing the factor can be obtained from the livers or the plasma of non-hepatectomized fetal or very young animals.
展开▼