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A pharmaceutical products and their use for preventing harmful side effects of oxazaphosphorine-type cytostatics

机译:药物产品及其在预防草氮磷型细胞抑制剂的有害副作用中的用途

摘要

The invention is related to a process for the treatment of humans suffering from undesired urotoxic side effects caused by cytostatically active alkylating agents administered to them against malign tumors, comprising administering a pharmacologically acceptable salt of a dithiodi-(alkane sulfonic acid) having the general formula IMAGE to the human treated with the cytostatically active alkylating agent, in an amount ranging from 20% of the weight of the alkylating agent to the highest tolerated dosage of the salt of the dithiodi-(alkane sulfonic acid), simultaneously or separately in combination with the alkylating agent.
机译:本发明涉及一种治疗人的方法,该人患有因对恶性肿瘤施予其的细胞抑制活性烷基化剂而引起的不希望的尿毒副作用,该方法包括给予具有通式的二硫代二(链烷磺酸)的药理学上可接受的盐。同时或分别在以下情况下对接受细胞抑制活性烷基化剂治疗的人的图像:烷基化剂重量的20%至二硫代二(烷磺酸)盐的最高耐受剂量。与烷基化剂结合。

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