Method of fractional quantitative determination of isoenzyme of lactic dehydrogenase

摘要

1,6-Dihydro nicotinamide adenine dinucleotide inhibits both H- type lactic dehydrogenase and M-type lactic dehydrogenase which are isoenzymes of lactic dehydrogenase, but the degree of inhibition thereof against H- type considerably differs from that against M-type. A ratio of H-type lactic dehydrogenase to M-type lactic dehydrogenase in serum can be measured by utilizing the difference of inhibition degree. Therefore we can diagnose the organ with trouble.