New composite fortimicina without Therapeutic activity for use as an intermediate in the preparation of fortimicina Derivatives with antibiotic activity and Process for preparing the3 - or - des - metilfortimicina B

摘要

Fortimicin AN is coproduced with fortimicin A, fortimicin B and a number of other minor factors in the fermentation of Micromonospora olivoasterospora ATCC Nos. 21819, 31009 or 31010. Structurally, fortimicin AN is 1-N-glycyl-3-O-demethylfortimicin B. The compound is useful as an intermediate for 3-O-demethylfortimicin B which is readily obtained by hydrolysis of fortimicin AN in base.