首页> 外国专利> Method for preparing Derivatives of 1 - (2 - (3 - indolil) - 1,1 - Dimethyl amino) - phenoxy) - 2 - or 3 - naftiloxi 2-propanol and their acid Addition salts

Method for preparing Derivatives of 1 - (2 - (3 - indolil) - 1,1 - Dimethyl amino) - phenoxy) - 2 - or 3 - naftiloxi 2-propanol and their acid Addition salts

机译:制备1-(2-(3-吲哚)-1,1-二甲氨基)-苯氧基)-2-或3-萘菲西2-丙醇及其酸加成盐的衍生物的方法

摘要

The compounds have the general Formula: IMAGE wherein Ar is phenyl or naphthyl, each X is an optional substituent independently chosen from a range of cyclic and non-cyclic aromatic and non-aromatic substituents, including alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, alkanyl, alkylsulphinyl, alkylthio, alkanamido, C3 to C6 optionally alkyl substituted cycloalkyl, optionally alkyl substituted cycloalkyl alkyl, each having up to 8 carbon atoms, phenyl, trifluoromethyl, nitro and cyanoalkyl, n indicates the number of X substituents and is from 0 to 2, and Het represents a nitrogen heterocycle, optionally containing one further hetero atom and optionally substituted with up to two ring substituents which are alkyl, N-lower alkyl carboxamido, N,N-dilower alkyl carboxamido, carbalkoxy wherein each of said foregoing groups contains up to 8 carbon atoms, oxo, or carboxamido.
机译:所述化合物具有通式:<图像>其中Ar是苯基或萘基,每个X是独立地选自环状和非环状芳族和非芳族取代基的任选取代基,包括烷基,烯基,炔基,烷氧基,烷氧基,烷烷基,烷基亚磺酰基,烷硫基,烷酰胺基,C 3至C 6各自为至多8个碳原子的任选烷基取代的环烷基,任选烷基取代的环烷基烷基,苯基,三氟甲基,硝基和氰基烷基,n表示X个取代基的数目并且是0至2,并且Het表示氮杂环,其任选地包含一个另外的杂原子并且任选地被至多两个环取代基取代,所述环取代基是烷基,N-低级烷基羧酰胺基,N,N-二低级烷基羧酰胺基,烷氧基。基团最多包含8个碳原子,氧代或羧酰胺基。

著录项

  • 公开/公告号AR225274A1

    专利类型

  • 公开/公告日1982-03-15

    原文格式PDF

  • 申请/专利权人 BRISTOL MYERS CO;

    申请/专利号AR19780272873

  • 发明设计人

    申请日1978-07-07

  • 分类号C07D209/14;

  • 国家 AR

  • 入库时间 2022-08-22 13:57:21

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