首页> 外国专利> FOERFARANDE Før FRAMSTAELLNING audio HYDROXIHALOGENBENSYLAMI nDeriv MED HOSTLINDRANDE SEKRETOLYTISK OCH formation of a YTAKTIVA AEMNEN UNDERLAETTANDE Effect

FOERFARANDE Før FRAMSTAELLNING audio HYDROXIHALOGENBENSYLAMI nDeriv MED HOSTLINDRANDE SEKRETOLYTISK OCH formation of a YTAKTIVA AEMNEN UNDERLAETTANDE Effect

机译:制造音频之前的步骤羟基卤代苯胺

摘要

Novel benzylamines of the formula I IMAGE in which the symbols R1 to R4, Hal and @ have the meaning given in Patent Claim 1, are prepared by introducing the group R2 or R4 into an appropriate secondary amine by the methods of N-alkylation. The compounds of the formula I and their physiologically tolerable acid addition salts with inorganic or organic acids have useful pharmacological properties, in particular a secretolytic and antitussive action in addition to an intensifying action on the production of the surfactant or anti-atelectasis factor of the alveoli.
机译:式I 的新型苄胺,其中符号R1-R4,Hal和@具有专利权利要求1中给出的含义,是通过将N2或R4基团通过N-烷基化的方法引入合适的仲胺中而制备的。式I化合物及其与无机或有机酸的生理上可耐受的酸加成盐除了对肺泡的表面活性剂或抗肺不张因子的产生产生增强作用外,还具有有用的药理特性,尤其是分泌分解和镇咳作用。 。

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