The present invention relates to a new technique and device for mass transport operation and physical separation, being substantially quantitative and involving selective barriers. According to the new technique, the mass transport through the selective barrier and physical separation are carried out in the same device. The device consists of a mixing-reservoir into which is fitted snugly a mixer-separator, having a channel in the vertical axis of the mixer-separator, the mixer-separator being provided with means for accumulating a gas pocket to decrease the pressure exerted on the barrier. The completely solid-free liquid passing through the selective barrier is removed by pushing in the mixer-separator, said liquid being accumulated in a collecting container. Typical examples of such selective barriers are: membrane, bed of adsorbent material, paper, plastic, glass and metal filters or any other porous material, hollow fibers etc. The new technique and device can be successfully utilized in any operation involving separation of solids from liquids and particularly useful in immunoassay, sterilization, ultra-filtration, desalination by reverse osmosis, etc.
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