Procedure for obtaining a complex theophylline sodi-ca n- (2-mercaptopropionyl) glycine

摘要

Procedure for obtaining the complex tofilina Sodium (- (2 - Mercap - topropionil) glycine, of Structural formula (i). Consists in reacting an aqueous solution of Theophylline with a MOL a MOL of Sodium hydroxide and with two moles of N - (2 - mercaptopionil) glycine, subsequently removing water by Vacuum Evaporation, by Spraying or by freeze-drying.The temperature at which the Reaction takes place is usually 60 to 70 degrees. For use in Pharmaceutical preparations by its bronchodilator Action and mucolytic.