Dental health compsn. contg. biotin antagonist - to inhibit growth of biotin dependent cariogenic microorganisms

摘要

Dental health prod. is a toothpaste, toothpowder, mouthwash, chewing gum, confection, tooth-coating concentrate or sustained-release buccal tablet contg. enough biotin antagonist (I) to prevent biotin uptake by microorganisms which cause dental caries, plaque and acid formation. Pref. (I) is a biotin inactivator and/or a biotin antimetabolite. (I) inhibit biotin which is an essential growth factor for the oral bacteria, so interfere with their development. They have no significant effect on the biotin store in the body.