neue eburnan oxime - ether - derivative und verfahren zur herstellung dieser verbindungen

摘要

The invention relates to optically active or racemic eburnane-oxime ethers of the formulae (Ia) and/or IMAGE (Ia) IMAGE (Ib) wherein R represents an alkyl group having 1 or 2 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms, and the configuration of the hydrogen in the 3-position and the R2 group is alpha , alpha and/or beta , beta or alpha , beta and/or beta , alpha and acid addition salts thereof. The new compounds show valuable pharmaceutical activities, thus are potent CNS-tranquillants, smooth muscle relaxants, sedatives and hypnotic agents, and can therefore be employed as active ingredients of pharmaceutical compositions, which are also within the scope of the present invention.