An IV chamber flow controller includes a plug integrally connected to the chamber and a flexible tube extending through the plug. A plunger rod is moved by a skirt which is rotatably mounted on the chamber and pinches off the tube to stop flow from the chamber. The skirt includes a crescent shaped groove for controlling movement of the plunger rod. A flow path from the IV chamber to an IV tube is straight and uninterrupted so that leakage and sterility problems are reduced.
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