Process for preparing substituted pregn 18 - 4 Jan - dionas 3.20 and specific compounds 18 and vinilidenopregn TSI ilpregn - - 4 - - - eno 3,20 Dione.

摘要

Process for preparing substituted pregn 18 - - 4 - - - dionas eno 3.20 and specific compounds 19 - - - - etinilpregn and vinilidenopregn 4 ene 3, 20 Dione, of General formula (i), in which Hydrogen and hydroxyl or Hydrogen; and Z is hidroxi.consiste or in making a proper 13 - (Acetoxy - 1 - 2 - propin Il - esteroi), lithium (Butyl) (1 - pentinil) cuprate, obtain a Group 13 - alenilo.Then SUPPRESS any protector ketal Group by Treatment with acid, and any Protective Group by hydrolysis of Ester, alcalina.de application in obtaining farmaceuticascon diuretic effect compositions