Method of preparation of the n - (2 - 5 - ((((dimethylamino) - methyl) - 2 - furanylmethyl) - thio) ethyl) - n '- methyl - 2 - nitro - 1,1 - ethene - diamine, and products of this preparation #

摘要

The invention relates to a process for the preparation of ranitidine of the formula: IMAGE which is characterised in that a thiol of the formula: IMAGE is reacted with an alkylating agent of the formula: IMAGE in which R1 denotes the group -CH2CH2L, where L represents a leaving group, and R2 represents a hydrogen atom or R1 and R2, together with the nitrogen atom to which they are attached, form an ethyleneimino group.