medicine for treatment of hyperglycemia, hyperlipaemia, hypertension, inflammatorischen disorders, pain and pyrexia by excitation of the central nervous system and of tumours

摘要

Pharmaceutical compositions for oral or parenteral administration comprises o-aminobenzoic acid derivatives of the formula: IMAGE wherein 1R denotes the group formed by removing OH from the 1 (alpha) or 1 (beta) position of arabinose, xylose, glucose, galactose, rhamnose or mannose, and 2R denotes H, Na, K, 1/2 mol. Mg, 1/2 mol. Ca, 1/3 mol. Al or methyl, together with a pharmaceutically acceptable diluent or carrier. The compositions have activity against hyperglycemia, hypertension, hyperlipemia, inflammatory diseases, pain, pyrexia and tumours. The compounds (1) may be prepared by reacting o- aminobenzoic acid with the appropriate saccharide in methanolic ammonium chloride.