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NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPETISCHE PROPERTIES, PHARMACEUTICAL PREPARATIONS WITH SUCH DERIVATIVES IN IT AND METHOD FOR THE ACTIVE INGREDIENTS OF PREPARATION.
NEW NUCLEOSIDE DERIVATIVES WITH ANTIHERPETISCHE PROPERTIES, PHARMACEUTICAL PREPARATIONS WITH SUCH DERIVATIVES IN IT AND METHOD FOR THE ACTIVE INGREDIENTS OF PREPARATION.
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机译:具有抗疱疹性质的新的核苷衍生物,具有这种衍生物的药物制剂及其活性成分的制备方法。
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摘要
This invention relates to novel nucleoside derivatives of the formula (I IMAGE and the pharmaceutically acceptable acid-addition salts thereof, wherein R and R1 are the same or different and stand for hydrogen or an optionally substituted acyl, optionally substituted cycloalkanoyl, optionally substituted aroyl or optionally substituted hetereoaroyl. Furthermore the invention relates to antiviral pharmaceutical compositions comprising these compounds, their use as antiviral agents and methods for the preparation of the compounds of the formula (I) and their pharmaceutically acceptable acid-addition salts. R and/or R1 may also be a blocking group, e.g. (4-methyoxytriphenylmethyl)methyl.
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