首页> 外国专利> Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides

Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides

机译:用于在酵母中表达外源基因的启动子,包含它们的质粒及其在生产多肽中的用途

摘要

Promoters capable of ensuring expression in yeast of genes coding for generally heterologous polypeptides are disclosed, which consist of a DNA fragment comprised between two restriction sites and having a definite nucleotide sequence, as well as the mutants and sub-fragment thereof.;Also disclosed are vector plasmids containing said promoters, transformed yeasts comprising said plasmids, and a process for preparing polypeptides and especially a 1,4,-β-N-acetylmuramidase.
机译:公开了能够确保在酵母中表达编码通常异源多肽的基因的启动子,其由包含在两个限制性位点之间并具有确定的核苷酸序列的DNA片段以及其突变体和亚片段组成。含有所述启动子的载体质粒,包含所述质粒的转化酵母,以及制备多肽,特别是1,4,-β-N-乙酰基村酰胺酶的方法。

著录项

  • 公开/公告号EP0184576A1

    专利类型

  • 公开/公告日1986-06-11

    原文格式PDF

  • 申请/专利权人 FINA RESEARCH S.A.;

    申请/专利号EP19850870171

  • 发明设计人 OBERTO JACQUES;DAVISON JOHN R.N.;

    申请日1985-12-05

  • 分类号C12N15/00;C07H21/04;C12N1/16;C12N1/18;C12P21/00;C12N9/80;

  • 国家 EP

  • 入库时间 2022-08-22 07:35:19

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