Useof cyclopentadienyl metal-acido complexes for the treatment of cancer and pharmaceutical compositions containing said complexes

摘要

This disclosure relates to the use of cytostatically active cyclopentadienyl metal-acido complexes for the treatment of transplanted tumor and pharmaceutical compositions containing said complexes. The organometallic compounds employed in the invention have the general formula: ##STR1## wherein M is Ti, Zr, Hf, V, Nb, Ta, Mo or W, Cp and Cp' are, e.g., cyclopentadienyl or substituted cyclopentadienyl radicals, Z is an optional straight-chain or branched bridging group having 1 to 3 C, Si or Ge atoms in the bridging chain and X and X' are, e.g., halogen, cyanate, isocyanate, thiocyanate, isothiocyanate, azide or phenylacetylide.