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Derivatives of M-glycosylated amides of carboxylic acids as a product for combating diseases of the rheumatism type

机译:羧酸的M-糖基化酰胺衍生物,用于抗风湿病

摘要

A method of combating rheumatic diseases which comprises administering to a patient afflicted therewith an amount effective to combat such disease of a compound of the formula IMAGE in which Z is a glycosyl radical bonded via the anomeric carbon atom, R1 is hydrogen or an optionally substituted hydrocarbon radical with up to 30 C atoms, which hydrocarbon radical is optionally interrupted by O, N or S, and R2 is hydrogen or an alkyl or aralkyl radical with up to 30 C atoms, which is optionally interrupted by O, N or S or substituted by an oxygen-containing group or halogen, with the proviso that COR1 is not an acyl group with 1-5 C atoms if R2 is alkyl with 10-20 C atoms.
机译:对抗风湿性疾病的方法,其包括向患该风湿性疾病的患者施用有效对抗这种疾病的量的式的化合物,其中Z为经由异头碳原子键合的糖基,R1为氢或任选地具有最多30个C原子的取代的烃基,该烃基可选地被O,N或S中断,R2是氢或具有多达30个C原子的烷基或芳烷基,其可选地被O,N或S中断或被含氧基团或卤素取代,条件是如果R2是具有10-20个碳原子的烷基,则COR1不是具有1-5个碳原子的酰基。

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