Bisbenzothiazine, bisbenzodiazine and bisquinoline pharmaceutical compositions and use

摘要

Compounds of the formula: ##STR1## wherein, R is H, alkyl, cycloalkyl, aryl or heteroaryl;PPR.sub.1 is H, alkyl, cycloalkyl, aryl, heteroaryl, substituted heteroaryl, aralkyl, substituted aryl, halo, OR.sup.2, SR.sup.2, NR.sub.2, CF.sub.3, NO.sub.2, CN, COOR.sup.2, CHO, SO.sub.3 H or SO.sub.2 NH.sub.2,PP whereinP PR.sup.2 is H, methyl, ethyl or propyl;P PY is ##STR2## Z is O, S, NH or CH.sub.2 ; X is ##STR3## wherein R.sup.2 is H, methyl, ethyl or propyl;PPn is 1-10, and pharmaceutically acceptable salts thereof have antiallergy and antiinflammatory activity.