NOVEL CEPHALOSPORINE DERIVATIVE HAVING IMPROVED PHARMACOKINETIC CHARACTERISTIC, ITS PRODUCTION AND DRUG COMPOSITION

摘要

Derivatives corresponding to the general formula: IMAGE in which: - R1, R2 and R3 denote H, or R1 and R2 denote H or CH3 and R3 = COOH or else IMAGE form a cyclobutyl group and R3 = COOH; - A and B are different and occupy the meta and para positions of the benzene nucleus; one denotes a hydroxyl group and the other is chosen from the groups IMAGE and the pharmaceutically acceptable salts and esters of the said derivatives. Use in therapeutics.