MICROBIOLOGICAL PRODUCTION OF HUMAN TISSUE PLASMINOGEN ACTIVATING FACTOR

摘要

Process for the preparation of human tissue plasminogen activator t - pa by culture of bacteria (e. coli) capable of ensuring a stable positioning of a plasmid containing the pl promoter of the bacteriophage lambda, the ribosome binding site of the gene of the bacteriophage lambda cii and the atg initiation codon, fused with the gene of the structure of the human tissue plasminogen activator and the conversion of the enzyme is thus obtained in its active form.