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AMINOO33CARDENOLIDES*THEIR MANUFACTURE AND MEDICINES CONTAINING THEM
AMINOO33CARDENOLIDES*THEIR MANUFACTURE AND MEDICINES CONTAINING THEM
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机译:氨基33碳酸钠*其制备和包含它们的药物
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摘要
Aminocardenolides of formula (I): IMAGE (I) in which R1, R2, R4, R5, and R6, which may be the same or different, each represents a hydrogen atom or a hydroxy, alkoxy or acyloxy group; R3 represents a lower alkyl, hydroxyalkyl, acyloxyalkyl, haloalkyl or ethylenedioxyalkyl group; R7 represents a hydrogen atom, or an alkyl or acyl group, and R8 represents a hydrogen atom, an alkyl group or an amino acid residue; a process for preparation of the compounds with the above formula by reaction of an oxo-3 genin with an ammonium salt in the presence of a borocyanohydride in an organic solvent. The aminocardenolides of formula (I) are useful especially for the treatment of cardiac ailments.
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