Method for preparing aqueous mixtures using VANILLIN and salts of carboxylic acids, which increase the Sugar content of the grapes before Harvest

• 1. 以纤维二糖或者纤维二糖与葡萄糖混合物为原料制备石墨烯的方法 [P] . 中国专利： CN108793131A . 2018-11-13
• 2. 用于制备1-脱氧-1-甲基氨基-D-葡萄糖醇2-(3,5-二氯苯基)-6-苯并噁唑羧酸盐的方法 [P] . 中国专利： CN113874359A . 2021-12-31
• 3. USE OF VANILLIN OR A CARBOXYLIC AND SALT TO INCREASE THE SUGAR LEVEL OF GRAPES [P] . NZ193526A . 1982-12-07

  机译： 使用香兰素或羧酸和盐来增加谷物的糖度

• 4. METHOD OF RIPENING OF GRAPES WITH VANILLIN OR SALTS OF CARBOXYLIC ACIDS [P] . IL59927A . 1983-09-30

  机译： 用香草醛或羧酸盐将葡萄成熟的方法

• 5. Compsn. for increasing sugar content of grapes and pineapples - contains 5-chloro-indazole-3-carboxylic acid or ester [P] . 法国专利： FR2417931B1 . 1985-03-22

  机译： Compsn。用于增加葡萄和菠萝的糖含量-包含5-氯-吲唑-3-羧酸或酯

• 1. Using benzene carboxylic acids to prepare zirconium-based catalysts for the conversion of biomass-derived furfural [J] . Huacong Zhou, Yufei Sha, Zhenhuan Xiao, 国际煤炭科学技术学报（英文） . 2018,第004期
• 2. Using benzene carboxylic acids to prepare zirconium-based catalysts for the conversion of biomass-derived furfural [J] . Huacong Zhou, Yufei Sha, Zhenhuan Xiao, 国际煤炭科学技术学报：英文版 . 2018,第004期
• 3. Coping with extremes:lowered myocardial phosphofructokinase activities and glucose content but increased fatty acids content in highland Eurasian Tree Sparrows [J] . Boyang Ding, Yuliang Zhao, Yanfeng Sun, 鸟类学研究：英文版 . 2021,第004期
• 4. Influence of Carboxylic Acid-Carboxylic Ester Ratio of Carboxylic Acid Ester Superplasticizer on Characteristics of Cement Mixtures [C] . G. Ferrari, T. Cerulli, P. Clemente, CANMET/ACI international conference on superplasticizers and other chemical admixtures in concrete . 2000
• 5. Cavity ring down: Construction, validation and experiments measuring the optical extinction of pure clays and their mixtures with salts and carboxylic acids under a range of atmospherically relevant conditions [D] . Attwood, Alexis Rae 2012
• 6. A mechanistic analysis of the increase in the thermal stability of proteins in aqueous carboxylic acid salt solutions. [O] . J. K. Kaushik, R. Bhat 1999
• 7. The development of unlike induced association-site models to study the phase behaviour of aqueous mixtures comprising acetone, alkanes and alkyl carboxylic acids with the SAFT-g Mie group contribution methodology [O] . Sadeqzadeh, Majid, Papaioannou, Vasileios, Dufal, Simon, 2015

• 1. BACKGROUND： Vibrio vulnifi cus inside the body could activate the NF-!B signaling pathwayand initiate the inflammatory cascade. The lung is one of the earliest organs affected by sepsisassociated with acute lung injury. High mobility group protein B1 （HMGB1） is an important late-actingpro-infl ammatory cytokine involving in the pathophysiology of sepsis. It is also involved in the injuryprocess in the lung, liver and intestine. There has been no report on the involvement of HMGB1 inVibrio vulnifi cus sepsis-induced lung injury.METHODS： Sixty rats were randomly divided into a normal control group （group A, n=10） anda Vibrio vulnificus sepsis group （group B, n=50）. Sepsis was induced in the rats by subcutaneousinjection of Vibrio vulnificus （concentration 6×108 cfu/mL, volume 0.1 mL/100g）） into the left lowerlimbs. The rats in group B were sacrifi ced separately 1, 6, 12, 24, and 48 hours after the infection.Their lungs were stored as specimens, lung water content was measured, and lung pathology wasobserved under a light microscope. The expressions of the HMGB1 gene and protein in the lungswere detected by RT-PCR and Western blot. Data were analyzed with one-way analysis of variance（ANOVA） and the LSD method for pair-wise comparison between the two groups. P〈0.05 wasconsidered statistically signifi cant.RESULTS： Compared to group A （0.652±0.177）, HMGB1 mRNA expression in the lungs ofgroup B was signifi cantly higher at 0 hour （1.161±0.358, P=0.013）, 24 hours （1.679±0.235, P=0.000）,and 48 hours （1.258±0.274, P=0.004） （P〈0.05）, and peaked at 24 hours. Compared to group A（0.594±0.190）, HMGB1 protein expression at 6 hours （1.408±0.567, P=0.026） after infection wassignificantly increased （P〈0. 05）, and peaked at 24 hours （2.415±1.064, P=0.000） after infection.Compared to group A （0.699±0.054）, lung water content was significantly increased at 6 hours（0.759±0.030, P=0.001）,12 hours （0.767±0.023, P=0.000）, 24 hours （0.771±0.043, P=0.000） and 48hours （0.789±0.137, P=0.000） after infection （P〈0.05）. Compared to group A, pathological changesat 12 hours in group B indicate marked pulmonary vascular congestion, interstitial edema andinfl ammatory infi ltration. Alveolar cavity collapse and boundaries of the alveolar septum could not beclearly identifi ed.CONCLUSION： Vibrio vulnifi cus sepsis can lead to injury in rat lungs, and increased HMGB1expression in lung tissue may be one of the mechanisms for injury from Vibrio vulnifi cus sepsis. [J] . Qiao-meng Qiu ,Zhong-wang Li ,Lu-ming Tang . 世界急诊医学杂志(英文) . 2011,第4期
• 2. Quantification and Comparison of Sugars, Carboxylic Acids and Vitamin C Components of Various Citrus Species by HPLC Techniques [J] . E. Kafkas ,S. Polatoz ,N. K. Koc . 农业科学与技术 . 2011,第002期
• 3. 门冬氨酸钾镁葡萄糖注射液中葡萄糖含量测定方法研究 [C] . 于丽芬 ,葛求富 . 2002年全国医院药学学术研讨会 . 2002
• 4. 5-氨基乙酰丙酸对油菜幼苗硫代葡萄糖甙等代谢产物的影响与种子硫甙葡萄糖甙含量的全基因组关联分析 [A] . Antony Maodzeka安东尼 . 2020