NOVEL DIPHENIC ACID MONOAMIDES HAVING ACTIVITY AS LEUKOTRIENE ANTAGONISTS,5-LIPOXYGENASE INHIBITORS AND MEDIATOR RELEASE INHIBITORS

摘要

The present invention provides various novel diphenic acid monoamide compounds, novel pharmaceutical compositions and methods of use thereof, as well as novel methods of synthesis therefor. The novel diphenic acid monoamides of the present invention are leukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.