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Substituted guanine nucleoside derivative, preparations made therefrom, as well as its use as a medicament
Substituted guanine nucleoside derivative, preparations made therefrom, as well as its use as a medicament
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机译:取代的鸟嘌呤核苷衍生物,由其制备的制剂及其在药物中的用途
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摘要
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are heteroatom-substituted-hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.
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