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Substituted guanine nucleoside derivatives, immune response enhancing preparations thereof, and method of enhancing an immune response
Substituted guanine nucleoside derivatives, immune response enhancing preparations thereof, and method of enhancing an immune response
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机译:取代的鸟嘌呤核苷衍生物,其免疫应答增强制剂以及增强免疫应答的方法
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摘要
7,8-Disubstituted guanosine nucleoside derivatives are found to be potent immune response enhancing agents in human and animal cells. 7-Substituents are heteroatom-substituted-hydrocarbyl radicals having a length greater than ethyl and less than about decyl. 8-Substituents are =O, =S, =Se and =NCN. Compositions and methods of use are also disclosed.
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