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Process for the preparation of zidovudine, as well as intermediates in the process
Process for the preparation of zidovudine, as well as intermediates in the process
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机译:齐多夫定的制备方法以及该方法的中间体
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摘要
This invention relates to a new synthetic process for the manufacture of zidovudine from the starting material D-xylose involving: i) Conversion of D-xylose to a 1-( beta -D-xylofuranosyl)thymine derivative; ii) 2 min -Deoxygenation of the thymine derivative; and iii) 3 min -Azidation of the 2 min -deoxy compound. r
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