Bacillus subtilis cells transformed by a hybrid plasmid, the separation of the precursor from the total proteins, the digestion of the precursor with the enzyme Factor Xa and finally the purification of the natural hGH thus obtained from the enzymatic hydrolysis mixture.;The growth hormone thus prepared has a purity of 100% or approximately 100% and is particularly useful for human treatment."/>
公开/公告号EP0321940A2
专利类型
公开/公告日1989-06-28
原文格式PDF
申请/专利权人 ENIRICERCHE S.P.A.;
申请/专利号EP19880121370
申请日1988-12-21
分类号C12N15/09;C12N15/18;C12P21/02;A61K37/36;
国家 EP
入库时间 2022-08-22 06:34:03