Method of manufacturing at least single-layer tubular blood vessel endoprosthesis, especially of a small internal diameter, and extruding nozzle for carrying out this method

摘要

The method comprises a first phase wherein a thermoplastic biological material is extruded through an axial passage in a nozzle onto a core which is capable to reduce its profile if exposed to an axial tension whereby a homogeneous uniform layer of said material is created on said core, further a second phase wherein the layer of biological material is hardened and dried on said core, or, optionally, to the hardenen and dried layer at least another layer is applied and fixed thereon, and, finally, a third phase wherein the layer of biological material, or a laminate, respectively, contracts and becomes loose on the core by axially tensioning the latter so that the tubular layer can be easily removed therefrom.